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KMID : 1007520130220010181
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Food Science and Biotechnology
2013 Volume.22 No. 1 p.181 ~ p.186
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Antioxidant and Antiproliferation Activities of Winter Cereal Crops before and after Germination
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Kim Hyun-Young
Lee Sang-Hoon
Hwang In-Guk
Woo Koan-Sik
Kim Kee-Jong
Lee Mi-Ja
Kim Dae-Joong
Kim Tae-Jip
Lee Jun-Soo
Jeong Heon-Sang
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Abstract
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This study investigated the changes in antioxidant and antiproliferation activities of germinated winter cereal crops, including oats, barley, rye, and wheat, to develop functional materials. The highest total polyphenol content was found post-germination at 3.97 mg gallic acid equiv./ g, which was 1.61-fold higher than the 2.46 mg gallic acid equiv./g in pre-germination barley. The flavonoid content was highly increased in wheat, which was 2.25-fold higher than 0.28 mg catechin equiv./g sample in pre-germination. The DPPH free radical scavenging activity (IC50) was the greatest in the post-germination barley at 1.67 mg/mL. The highest ascorbic acid equivalent antioxidant capacity (7.43 mg AA eq/g sample) was obtained from postgermination barley, while its pre-germination capacity was 5.44 mg AA eq/g sample. The post-germination oats ethanol extract had a higher antiproliferation effect on HepG2 and HCT-116 cell lines than the pre-germination extract. The cell viability of the HepG2 and HCT-116 cell lines exposed to the post-germination oats was 19.98 and 11.81% at 3.0 mg/mL, respectively.
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KEYWORD
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wheat, barley, germination, antioxidant activity, anticancer
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